Author

Prashant K. Sharma

University Medical Center GroningenORCID 0000-0002-8342-8939Unclaimed ORCID profile · follow to get notified of new preprints

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Prashant Kumar Sharma1 paper

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Janette Kay BurgessiD· 2 shared Martin C. HarmseniD· 2 shared Barbro N. MelgertiD· 1 shared Eric S. WhiteiD· 1 shared Fenghua ZhaoiD· 1 shared Irene H. HeijinkiD· 1 shared Karim Christian El KasmiiD· 1 shared Matthew James ThomasiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBioengineering

Janette Kay BurgessORCID

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2 papers

Recent·Most cited

Fibroblast alignment is governed by stiffness interfaces in hydrogels.

R. J. B. Dijkstra, Janette Kay Burgess, Xenos Petridis, Prashant K. Sharma, Martin C. Harmsen

This study shows fibroblasts align differently at soft/soft vs. soft/stiff hydrogel interfaces, with increased myofibroblast differentiation at stiff interfaces due to mechanical cues alone.

Cell Reports Physical Science · Jul 9, 2026Peer-reviewedBioengineering

Contrasting responses of control and fibrotic lung fibroblasts to fibrotic stimuli: the role of osteoprotegerin in extracellular matrix remodeling

Yanzhe Liu, Mehmet Nizamoglu, Fenghua Zhao, Theo Borghuis, Taco Koster, Prashant Kumar Sharma, Martin C. Harmsen, Matthew James Thomas, Eric S. White, Karim Christian El Kasmi, Irene H. Heijink, Barbro N. Melgert, Janette Kay Burgess

This study compares OPG secretion and ECM remodeling in control and fibrotic lung fibroblasts under fibrotic conditions, finding opposite responses in matrix stiffness and collagen fiber properties.

bioRxiv · Feb 20, 2025 · PreprintCell Biology