Molecular BiologybioRxivPreprint
AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
Steffen Henning Raun, Mona Sadek Ali, Xiuqing Han…·Lykke Sylow
This study shows that AMPK is upregulated in human cachectic muscle and that AMPK deficiency in mice worsens cancer-induced metabolic dysfunction and cachexia.