Kirsten A. Fairfax

The paper identifies expressed endogenous retroviral element long terminal repeats (ERV LTRs) in devil facial tumour cells and validates them as potential vaccine targets.

The paper examines sex differences in the immune system at the single-cell level, identifying sex-biased genes and eQTLs linked to autoimmune diseases.

This paper develops a field-deployable diagnostic test for DFT1 and DFT2 using SHERLOCK to detect DNA in attomolar range and non-invasive samples.

This study uses prime editing to correct a common TPP1 mutation in cultured cells and eVLPs, achieving on-target editing efficiencies of up to 27.36% and 12.6% in vivo.

This study evaluates in silico variant prediction tools for cancer genes, finding gene-specific performance issues and recommending validation for individual genes.

This study compares generative AI models for protein design, finding structural models produce more confident structures but less diversity, while language models generate more diverse proteins with lower structural confidence.

This paper reviews functional genomic assays for telomere biology disorder genes to assess their utility in variant classification.