Dengue virus harnesses mosquito Syntenin to load and secrete viral RNA into salivary exosomes
Florian Rachenne, Norman Schneider, Félix Rey-Cadilhac, Idalba Serrato-Pomar, Lauryne Pruvost, Laura Di Pietro, Jacques Dainat, Audrey Vernet, Chantal Cazevieille, Aurélie Ancelin, Joséphine Lai‐Kee‐Him, Sander Jansen, Elliott F. Miot, Jérémy Fraering, Laurianne Simon, , Julien Pompon
This study identifies how dengue virus uses mosquito Syntenin to package and secrete viral RNA into salivary exosomes, revealing a mechanism for viral RNA incorporation into extracellular vesicles.
Proceedings of the National Academy of Sciences · Mar 16, 2026Peer-reviewedMicrobiology