Julien Pompon

This study identifies sfRNA in mosquito saliva that enhances orthoflavivirus transmission by inhibiting MDA5-mediated interferon response in human skin cells.

This paper introduces BIRD-Seq, a dsRNA detection and sequencing pipeline using engineered B2 protein and nanopore sequencing, achieving sub-ng mL-1 sensitivity and enabling virus identification without RNA extraction.

This study uses single-cell RNA-sequencing to analyze skin responses to West Nile virus-infected mosquito bites, identifying fibroblasts as key cells restricting viral transmission.

This study identifies how dengue virus uses mosquito Syntenin to package and secrete viral RNA into salivary exosomes, revealing a mechanism for viral RNA incorporation into extracellular vesicles.

The paper presents a single-nucleus RNA sequencing atlas of Aedes aegypti mosquitoes, identifying novel cell types and sexual dimorphism in gene expression across tissues.

The paper compares TMUV cluster 1 and 2 strains, finding cluster 2 has higher replication efficiency in human cells and induces stronger innate immune responses.

This study identifies sphingomyelins in mosquito salivary extracellular vesicles that enhance flavivirus transmission by altering the host lipidome and increasing viral protein levels.

This study shows that arboviruses reduce salivation in Aedes aegypti mosquitoes by disrupting salivary gland organization, potentially enhancing virus transmission.

This study demonstrates that West Nile virus is transmitted among mosquitoes via infectious excreta, revealing a new transmission route and its epidemiological impact.

This study identifies YBX1 as a host factor that interacts with dengue virus nucleocapsid and is required for efficient viral assembly and secretion.