Thymidine kinase-expressing yellow fever 17D reporter virus facilitates prodrug activation and bioorthogonal labelling of infected cells
Michael Bright Yakass, Sander Jansen, Viktor Lemmens, Lorena Sánchez-Felipe, Johan H. Neyts, Nathan W. Luedtke, Osbourne Quaye, Kai Dallmeier
This study develops a yellow fever 17D reporter virus expressing thymidine kinase to enable prodrug activation and bioorthogonal labeling of infected cells for tracking viral replication and tissue tropism.
Heliyon · Mar 30, 2026Peer-reviewedMicrobiology