NeuroscienceNature NeurosciencePeer-reviewed
Embryonic motor neuron programming factors reactivate immature gene expression and suppress ALS pathologies in postnatal motor neurons
Emily R. Lowry, Tulsi Patel, Jonathon A. Costa…·Hynek Wichterle
This study re-expresses embryonic motor neuron factors in mature neurons to reverse age-related degeneration and reduce ALS symptoms in a mouse model.
6 citations