Ying Lü

This study screens antimicrobial peptides using a mechanism-driven approach, identifying seven peptides with membrane-targeting and pore-forming activity that show antimicrobial efficacy with low cytotoxicity.

This study develops a single-molecule technique to investigate cytoplasmic tail dynamics of membrane receptors in living cells, revealing ligand-induced activation mechanisms of β2AR.

This paper introduces a method using liposome encapsulation to improve cryo-EM structural determination by preserving macromolecules in a near-native environment, reducing disassembly and orientation artifacts.