Author

Miloš Tišma

Boston Children's HospitalORCID 0000-0002-8449-142XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Organism:C. elegans· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

Alejandro Martín-GonzáleziD· 1 shared Anders BarthiD· 1 shared Anjana BadrinarayananiD· 1 shared Brian T. AnalikwuiD· 1 shared Cees DekkeriD· 1 shared Gianluca Kemps· 1 shared Hammam AntariD· 1 shared Joseph J. LoparoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

Alejandro Martín-GonzálezORCID

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2 papers

Recent·Most cited

Chromosome topology gates productive RecA homology search

Miloš Tišma, Sourav Bhattacharyya, Seungwoo Chang, Taekjip Ha, Anjana Badrinarayanan, Joseph J. Loparo

The paper shows DNA supercoiling selectively enhances productive homology search by RecA filaments in Caulobacter crescentus, independent of DNA compaction.

bioRxiv · Jul 20, 2026 · PreprintBiophysics

DNA supercoiling enhances DNA condensation by ParB proteins

Alejandro Martín-González, Miloš Tišma, Brian T. Analikwu, Anders Barth, Richard Janissen, Hammam Antar, Gianluca Kemps, Stephan Gruber, Cees Dekker

This study shows DNA supercoiling enhances ParB-DNA condensation, forming partition complexes at lower ParB concentrations than on relaxed DNA.

Nucleic Acids Research · Oct 8, 2024Peer-reviewedBiophysics