Author

Sebastian Rune Nielsen

Icahn School of Medicine at Mount SinaiORCID 0000-0002-8449-476XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Alessia BaccariniiD· 1 shared Alexander TepperiD· 1 shared Bhavya SinghiD· 1 shared Brian D. BrowniD· 1 shared Chiara FalcomatàiD· 1 shared Divya Chhamalwan· 1 shared Gürkan MollaogluiD· 1 shared Hunter T. Potak· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alessia BaccariniORCID

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1 paper

Recent·Most cited

Plasminogen activator inhibitors orchestrate the immunosuppressive tumor microenvironment in pancreatic cancer

Chiara Falcomatà, Sebastian Rune Nielsen, Maximilian M. Schaefer, Bhavya Singh, Alexander Tepper, Divya Chhamalwan, Hunter T. Potak, Maxime Dhainaut, Gürkan Mollaoglu, Matthew D. Park, Miriam Mérad, Alessia Baccarini, Brian D. Brown

This study identifies Serpinb2 and Serpine1 as key factors in pancreatic cancer that remodel the tumor microenvironment to promote immune evasion and tumor progression.

bioRxiv · Jun 11, 2025 · PreprintCancer Biology