Author

Leonard McMillan

University of North Carolina at Chapel HillORCID 0000-0002-8453-0847Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Leonard McMillan3 papers

Biology Disciplines

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Genetics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:database / resource· 1 Approach:experimental assay· 1 Research Focus:genome assembly· 1 Approach:graph neural network· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Fernando Pardo‐Manuel de VillenaiD· 3 shared John R. ShorteriD· 3 shared Ginger D. ShawiD· 2 shared Maya L. Najarian· 2 shared Timothy A. BelliD· 2 shared William S. J. ValdariD· 2 shared A. Wesley BurksiD· 1 shared Abraham A. PalmeriD· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetics

Fernando Pardo‐Manuel de VillenaORCID

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Author profile →

3 papers

Recent·Most cited

Content and performance of the MiniMUGA genotyping array, a new tool to improve rigor and reproducibility in mouse research

John Sebastian Sigmon, Matthew W Blanchard, Ralph Steven Baric, Timothy A. Bell, Jennifer Brennan, Gudrun A. Brockmann, A. Wesley Burks, J. Mauro Calabrese, Kathleen M. Caron, Richard E. Cheney, Dominic J. Ciavatta, Frank L. Conlon, David B. Darr, James E. Faber, Craig L. Franklin, , Fernando Pardo‐Manuel de Villena

The paper introduces MiniMUGA, a genotyping array for mouse genetic QC, showing it effectively discriminates strains, detects genetic constructs, and identifies sex chromosome abnormalities.

Genetics · Oct 17, 2020Peer-reviewedGenetics

The Collaborative Cross Graphical Genome

Hang Su, Ziwei Chen, Jaytheert Rao, Maya L. Najarian, John R. Shorter, Fernando Pardo‐Manuel de Villena, Leonard McMillan

The paper introduces a graph-based pangenome representation for the Collaborative Cross mouse genetic reference population, enabling analysis of multiple genomes in a unified framework.

bioRxiv · Nov 29, 2019 · PreprintBioinformatics

A diallel of the mouse Collaborative Cross founders reveals strong strain-specific maternal effects on litter size

John R. Shorter, Paul L. Maurizio, Timothy A. Bell, Ginger D. Shaw, Darla R. Miller, Terry J. Gooch, Jason S Spence, Leonard McMillan, William S. J. Valdar, Fernando Pardo‐Manuel de Villena

The paper analyzes reproductive success in mouse Collaborative Cross founder strains, finding that dam strain has a larger effect on litter size than sire strain.

G3 Genes Genomes Genetics · Mar 15, 2019Peer-reviewedGenetics