Ginger D. Shaw

The paper identifies immune mediators linking host susceptibility loci to disease severity across SARS-CoV and SARS-CoV-2 infections.

The paper updates the MiniMUGA genotyping array's bioinformatic pipeline to enhance genetic QC in laboratory mice by improving marker annotation, consensus genotypes, and report usability.

The paper identifies a genetic locus associated with coronavirus disease susceptibility in mice and shows its relevance to human severe COVID-19 outcomes.

This study identifies a Themis mutation as a genetic contributor to peanut-induced anaphylaxis in CC027 mice through genetic mapping and immunological analysis.

The paper identifies MBD1 as a regulator of homeostatic IgG1 levels and marginal zone B cell differentiation through a genetic screen in Collaborative Cross mice.

The paper identifies genetic drivers of protein phosphorylation using multi-omics data from mouse tissues, revealing novel interactions and targets of PDK1 in obesity and diabetes.

This study identifies host-pathogen genetic interactions influencing tuberculosis susceptibility using a genetically diverse mouse panel and Mtb mutants.

The paper assesses cocaine-induced locomotor activation in 20 inbred mouse substrains from six lineages, identifying significant phenotypic differences that could inform genetic studies of addiction.

The paper analyzes liver proteomes across three genetically diverse mouse populations to understand how genetic variation influences protein abundance and its relationship to phenotypes.

The paper identifies genetic factors influencing immune cell populations in lung tissue and their predictive value for influenza outcomes in Collaborative Cross mice.

The paper introduces MiniMUGA, a genotyping array for mouse genetic QC, showing it effectively discriminates strains, detects genetic constructs, and identifies sex chromosome abnormalities.

This study identifies genetic factors influencing antipsychotic-induced adverse reactions in mice using RIX lines, finding strong strain and treatment interactions for behavioral phenotypes.

The paper uses Collaborative Cross mice to identify genetic loci and candidate genes associated with epilepsy traits, providing resources for studying seizure outcomes and developing new therapies.

The paper analyzes reproductive success in mouse Collaborative Cross founder strains, finding that dam strain has a larger effect on litter size than sire strain.

The paper uses a diallel analysis in mice to study how host genetics affect response to influenza A virus, identifying Mx1-dependent and independent heritable effects on weight loss.