Michael Schmid

GenomeCompendium is a database that integrates repeat, assembly quality, and functional content data from complete prokaryotic genomes to improve genome annotations and analyze taxonomic coverage.

ReCycled identifies and resets the start of circular bacterial chromosomes to improve comparative genomics analyses.

The paper introduces circAID-p-seq, a PCR-free method for phospho-RNA sequencing, and demonstrates its application in ribosome profiling to study RNA-protein interactions.

The paper uses long-read sequencing to assemble complete genomes from low-complexity microbial communities, revealing strain diversity and active phage systems.

The paper demonstrates that complex prokaryotic genomes with long, near-identical repeats require very long reads and specialized assemblers for accurate de novo assembly.

The paper develops an integrative proteogenomics strategy to improve prokaryotic genome annotation by combining multiple resources and experimental data, identifying novel ORFs and correcting errors.