Vincent Somerville

Uncovering novel phage defense systems through genomic island analysis in Streptococcus thermophilus

This study identifies novel antiviral defense systems in Streptococcus thermophilus by analyzing genomic islands, revealing previously uncharacterized systems and highlighting their role as reservoirs of bacterial immunity.

Microbial community dynamics in a traditional Swiss mountain cheese over 142 years of cheesemaking

This study analyzes microbial community changes in traditional Swiss cheese over 142 years, showing shifts linked to production practices and antibiotic use.

Predictable adaptive evolution of a phage endolysin through substrate recognition optimization

This study shows how endolysins adapt predictably through mutations that enhance substrate recognition, despite functional trade-offs and some variability in evolutionary paths.

ReCycled: A Tool to Reset the Start of Circular Bacterial Chromosomes

ReCycled identifies and resets the start of circular bacterial chromosomes to improve comparative genomics analyses.

Strain-level and phenotypic stability contrasts with plasmid and phage variability in water kefir communities

This study examines microbial community stability and variability in water kefir, finding species-level stability but plasmid and phage diversity across generations and households.

Genomic and phenotypic imprints of microbial domestication on cheese starter cultures

This study examines cheese starter cultures to determine if they show signs of microbial domestication, finding low genetic diversity, taxonomic stability, and evidence of genome decay.

An integrated model system to gain mechanistic insights into biofilm formation and antimicrobial resistance development in Pseudomonas aeruginosa MPAO1

The paper validates a model system to identify genes involved in biofilm formation and antibiotic resistance in Pseudomonas aeruginosa MPAO1 using genomics and experimental approaches.

Long read-based de novo assembly of low complex metagenome samples results in finished genomes and reveals insights into strain diversity and an active phage system

The paper uses long-read sequencing to assemble complete genomes from low-complexity microbial communities, revealing strain diversity and active phage systems.