Author

Kavita A. Iyer

Virginia Commonwealth UniversityORCID 0000-0002-8476-0036Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Montserrat SamsóiD· 1 shared Takashi MurayamaiD· 1 shared Takuya KobayashiiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Montserrat SamsóORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

BiochemistryStructurePeer-reviewedDec 20, 2024

Dantrolene inhibition of ryanodine receptor 1 carrying the severe malignant hyperthermia mutation Y522S visualized by cryo-EM

Kavita A. Iyer, Takuya Kobayashi, Takashi Murayama, Montserrat Samsó

This study uses cryo-EM to visualize how dantrolene inhibits the Y522S RyR1 mutant, revealing its binding site and mechanism of action in preventing malignant hyperthermia.

9 citations

humancryo-EM

𝕏 PostBluesky