Author

Honglei Zhou

St. Jude Children's Research HospitalORCID 0000-0002-8477-7153Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

A Wang· 1 shared Amar J. GajjariD· 1 shared Barbara JonchèreiD· 1 shared Brandon M. Bianski· 1 shared Burgess B. FreemaniD· 1 shared Giles W. RobinsoniD· 1 shared Jingjing LiuiD· 1 shared Jiyang YuiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A Wang

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1 paper

Recent·Most cited

Hidden-driver inference reveals synergistic brain-penetrant therapies for medulloblastoma

Jingjing Liu, Yang Xu, Mingrui Zhu, Xinran Dong, Honglei Zhou, Brandon M. Bianski, Barbara Jonchère, Wenwei Lin, Xiang Fu, Sheetal Bhatara, Jiyuan Yang, Song-Eun Lim, Lei Yang, Burgess B. Freeman, A Wang, , Jiyang Yu

The paper introduces SINBA, a computational framework that identifies synergistic, brain-penetrant drug combinations for high-risk medulloblastoma, validating several candidates in preclinical models.

bioRxiv · Nov 20, 2025 · PreprintCancer Biology