Author

Diego de Miguel

ORCID 0000-0002-8486-8514Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

Álvaro PeñaiD· 2 shared Diego CasabonaiD· 2 shared Juan Martínez-OlivániD· 2 shared Alexandre López· 1 shared Alexandre López-Gavín· 1 shared Alfonso Toro-CórdovaiD· 1 shared Ana Gallego-Lleyda· 1 shared Ana Larraga· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMolecular Biology

Álvaro PeñaORCID

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2 papers

Recent·Most cited

A complete approach for circRNA therapeutics from purification to lyophilized delivery using novel ionizable lipids

Esther Broset, Verónica Lampaya, Ana Larraga, Víctor Navarro, Alexandre López-Gavín, Diego de Miguel, Álvaro Peña, Juan Martínez-Oliván, Diego Casabona

This paper develops a complete approach for circRNA therapeutics, including purification, lipid nanoparticle formulation with novel ionizable lipids, and lyophilization to improve stability and delivery.

International Journal of Molecular Sciences · May 27, 2025Peer-reviewedMolecular Biology

Multicomponent Thiolactone-Based Ionizable Lipid Screening Platform for an Efficient and Tunable mRNA Delivery to the Lungs

Álvaro Peña, Juan Heredero, Beatriz Blandín, Elena Mata, Diego de Miguel, Alfonso Toro-Córdova, Teresa Alejo, Diego Casabona, Alexandre López, Ana Gallego-Lleyda, Esther Pérez‐Herrán, Juan Martínez-Oliván, Javier Giménez-Warren

This paper develops a lipid screening platform to identify efficient and tunable ionizable lipids for mRNA delivery to the lungs, resulting in a lipid that enhances protein expression and shows selective lung targeting.

Communications Chemistry · Apr 15, 2025Peer-reviewedBiochemistry