Author

Alfonso Toro-Córdova

ORCID 0000-0002-0087-7780Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Juan Martínez-OlivániD· 2 shared Alexandre López· 1 shared Álvaro PeñaiD· 1 shared Ana Gallego-Lleyda· 1 shared Beatriz Blandín· 1 shared Carlos MatuteiD· 1 shared Diego CasabonaiD· 1 shared Diego de MigueliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBioengineering

Juan Martínez-OlivánORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Enhancement of mRNA translation efficiency through 5'-UTR engineering

Esther Broset, Irene Blasco-Machín, Verónica Lampaya, Carlos Matute, Alfonso Toro-Córdova, Juan Martínez-Oliván

This study enhances mRNA translation efficiency by engineering Kozak repeats in the 5'-UTR, showing improved expression in both cell culture and mice.

bioRxiv · Sep 30, 2025 · PreprintBioengineering

Multicomponent Thiolactone-Based Ionizable Lipid Screening Platform for an Efficient and Tunable mRNA Delivery to the Lungs

Álvaro Peña, Juan Heredero, Beatriz Blandín, Elena Mata, Diego de Miguel, Alfonso Toro-Córdova, Teresa Alejo, Diego Casabona, Alexandre López, Ana Gallego-Lleyda, Esther Pérez‐Herrán, Juan Martínez-Oliván, Javier Giménez-Warren

This paper develops a lipid screening platform to identify efficient and tunable ionizable lipids for mRNA delivery to the lungs, resulting in a lipid that enhances protein expression and shows selective lung targeting.

Communications Chemistry · Apr 15, 2025Peer-reviewedBiochemistry