BioengineeringSignal Transduction and Targeted TherapyPeer-reviewed
Rapid CAR screening and circRNA-driven CAR-NK cells for persistent shed-resistant immunotherapy
Joo-Yoon Chung, Jisu Hong, Su‐Min Yee…·Mihue Jang
This paper develops a method to create CAR-NK cells resistant to antigen shedding using circRNA and a novel scFv, showing comparable in vivo efficacy to lentiviral CAR-NK cells.
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