Author

Jisu Hong

Seoul National UniversityORCID 0000-0002-2452-4824Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Assay:multiome· 1 Assay:proteomics· 1

Frequent Co-Authors

Chang-Han LeeiD· 2 shared Byung Joon LeeiD· 1 shared Byung‐Soo KimiD· 1 shared Chang Kyung KangiD· 1 shared Dahye Lee· 1 shared Dohyun HaniD· 1 shared Hang‐Rae KimiD· 1 shared Hayoung KwoniD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBioengineering

Chang-Han LeeORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Staged heavy-chain filtering enables Fab discovery from combinatorially intractable library spaces

Youngju Kim, Hayoung Kwon, Jisu Hong, Chang Kyung Kang, Wan Beom Park, Hang‐Rae Kim, Chang-Han Lee

This paper introduces a staged approach to Fab discovery by sequentially enriching heavy-chain variants and remating them with light-chain repertoires to overcome combinatorial complexity in antibody library screening.

Journal of Biological Engineering · Oct 30, 2026Peer-reviewedBioengineering

Dual-targeted nanoparticles enable the ex vivo generation of cytotoxic and phagocytic CAR effector cells

Jisu Hong, Jinwoong Lim, Minho Park, Jimin Song, Byung Joon Lee, Miyoung Park, Min‐Kyoo Shin, Hyungseok Seo, Hyoung Jin Kang, Byung‐Soo Kim, Dohyun Han

This study develops dual-targeted lipid nanoparticles to enhance the ex vivo generation of CAR-T cells and CAR-monocytes, showing improved cytotoxic and phagocytic activity.

bioRxiv · Sep 22, 2026 · PreprintBiochemistry

Rapid CAR screening and circRNA-driven CAR-NK cells for persistent shed-resistant immunotherapy

Joo-Yoon Chung, Jisu Hong, Su‐Min Yee, Hye Won Lim, Dahye Lee, Sang-Won Yoon, Seung-Hwan Lee, Yu-Jin Jung, Seung Hun Shin, Song Cheol Kim, Chang‐Han Lee, Mihue Jang

This paper develops a method to create CAR-NK cells resistant to antigen shedding using circRNA and a novel scFv, showing comparable in vivo efficacy to lentiviral CAR-NK cells.

Signal Transduction and Targeted Therapy · Apr 10, 2026Peer-reviewedBioengineering