Author

Sebastian E. Brauchi

Austral University of ChileORCID 0000-0002-8494-9912Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 2 Bioinformatics· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:proteomics· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Camila A. QuerciaiD· 2 shared Gonzalo RiadiiD· 2 shared Juan C. OpazoiD· 2 shared Luka RobesoniD· 2 shared Cristian Montecinos· 1 shared Cristóbal UribeiD· 1 shared Deny Cabezas-BratescoiD· 1 shared Ella MatamalaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersEvolutionary Biology

Camila A. QuerciaORCID

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Author profile →

4 papers

Recent·Most cited

Mechanosensitive channels dominate the minimal ion channelrepertoire in prokaryotes

Cristóbal Uribe, Luciano Pena, Samuel Morales-Navarro, Sebastian E. Brauchi, Gonzalo Riadi, Juan C. Opazo, Wendy González

The paper identifies five ion channel architectures essential for prokaryotic viability, with mechanosensitive channels being the most abundant.

Biophysical Journal · Sep 4, 2026Peer-reviewedBiophysics

Canonical G-protein coupled receptors of vascular plants

Valentina Fernandez Figueroa, Camila A. Quercia, Jan Gallastegui, Luka Robeson, Sebastian E. Brauchi

The paper identifies GCR1 as the sole GPCR in vascular plants through phylogenetic and bioinformatic analysis, suggesting its role in root hair function.

Plant Physiology and Biochemistry · May 29, 2026Peer-reviewedEvolutionary Biology

An Evolutionary Novelty in TRPV1 Functional Regulation: Characterization of a Dominant-Negative Isoform Exclusive to Catarrhine Primates

Sofía Cancino, Deny Cabezas-Bratesco, Ella Matamala, Julia M. York, Kattina Zavala, Cristian Montecinos, Sebastián Bustamante-Villarreal, R. Maldonado, Gonzalo Riadi, Sebastian E. Brauchi, Juan C. Opazo

The paper identifies a dominant-negative TRPV1 splice variant unique to catarrhine primates, which inhibits canonical TRPV1 function by preventing its membrane localization.

bioRxiv · Jan 24, 2025 · PreprintEvolutionary Biology

Evolutionary and Structural Bioinformatics Reveal GPR89 as a Conserved Solute Carrier Transporter

Camila A. Quercia, Luka Robeson, Sebastian E. Brauchi

This study uses bioinformatics to show GPR89 is a conserved solute carrier transporter, not a GPCR, with structural and evolutionary insights across eukaryotes.

Computational and Structural Biotechnology Journal · Jan 1, 2025Peer-reviewedBioinformatics