Author

Kattina Zavala

Universidad San SebastiánORCID 0000-0002-6583-3500Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Organism:non-human primate· 1

Frequent Co-Authors

Juan C. OpazoiD· 3 shared R. MaldonadoiD· 3 shared Gonzalo Antonio MardonesiD· 2 shared Catalina Méndez· 1 shared Consuelo Jalife· 1 shared Cristian MontecinosiD· 1 shared Cristian Montecinos· 1 shared David A. Brown‐Brown· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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3 shared papersEvolutionary Biology

Juan C. OpazoORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

RNA-DNA triplex-forming miRNAs define an evolutionarily recent chromatin regulatory mechanism

Michell Martin, Consuelo Jalife, Catalina Méndez, Cristian Montecinos, David A. Brown‐Brown, Francisca Díaz-Tejeda, Valeria Caffi, Kattina Zavala, Fabian Kugler, Loreto Molina-Gonzalez, Guillermo Valenzuela, Gernot Längst, Gonzalo Antonio Mardones, Roberto Munita, Juan C. Opazo, R. Maldonado

The paper identifies RNA-DNA triplex-forming miRNAs in human cells and shows they are evolutionarily recent and associated with Ago2-chromatin interactions.

bioRxiv · Jun 5, 2026 · PreprintMolecular Biology

Evolutionary history and functional divergence of hydroxycarboxylic acid receptors in primates

Juan C. Opazo, L. Felipe Barros, Kattina Zavala, R. Maldonado, Gonzalo Antonio Mardones

This study investigates the evolutionary history and functional divergence of HCAR2 and HCAR3 in primates, finding multiple duplication events in apes and functional specialization of HCAR3.

Genome Biology and Evolution · May 26, 2026Peer-reviewedEvolutionary Biology

An Evolutionary Novelty in TRPV1 Functional Regulation: Characterization of a Dominant-Negative Isoform Exclusive to Catarrhine Primates

Sofía Cancino, Deny Cabezas-Bratesco, Ella Matamala, Julia M. York, Kattina Zavala, Cristian Montecinos, Sebastián Bustamante-Villarreal, R. Maldonado, Gonzalo Riadi, Sebastian E. Brauchi, Juan C. Opazo

The paper identifies a dominant-negative TRPV1 splice variant unique to catarrhine primates, which inhibits canonical TRPV1 function by preventing its membrane localization.

bioRxiv · Jan 24, 2025 · PreprintEvolutionary Biology