Juan C. Opazo

The paper identifies five ion channel architectures essential for prokaryotic viability, with mechanosensitive channels being the most abundant.

This study investigates the evolution of ion channels during vertebrates' transition from water to land, finding adaptive changes in specific gene families critical for terrestrial physiology.

The paper identifies RNA-DNA triplex-forming miRNAs in human cells and shows they are evolutionarily recent and associated with Ago2-chromatin interactions.

This study investigates the evolutionary history and functional divergence of HCAR2 and HCAR3 in primates, finding multiple duplication events in apes and functional specialization of HCAR3.

This study analyzes globin gene evolution in cartilaginous fish using genomic and transcriptomic data, revealing gene loss, retention, and expression patterns compared to bony vertebrates.

The paper identifies positive selection in insulin, insulin receptor, and inceptor genes in hystricognath rodents, suggesting adaptive changes in the insulin signaling pathway.

The paper identifies a dominant-negative TRPV1 splice variant unique to catarrhine primates, which inhibits canonical TRPV1 function by preventing its membrane localization.

This study identifies MAO C as a new MAO gene family member in non-tetrapod jawed vertebrates and shows its enzymatic similarity to human MAO A.

The paper uses phylogenetic analysis of primate genomes to show that trichromatic color vision evolved independently in apes and Old World monkeys.