Author

Shangli Cheng

Karolinska InstitutetORCID 0000-0002-8501-086XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 4 Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Qiaolin DengiD· 4 shared Eva HedlundiD· 3 shared Julio Aguila BeniteziD· 3 shared Ming Cao· 2 shared Nigel KeeiD· 2 shared Dongqing LiiD· 1 shared Eva K. HerteriD· 1 shared Irene MeiiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersNeuroscience

Qiaolin DengORCID

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4 papers

Recent·Most cited

A linear regression model predicts human brain ageing and reveals differential neuronal biological ageing relevant for Parkinson's disease susceptibility

Shangli Cheng, Julio Aguila Benitez, Mélanie Lebœuf, Menghan Wang, Irene Mei, Silvia Gómez Alcalde, Qiaolin Deng, Rosario Sánchez‐Pernaute, Eva Hedlund

The paper develops a linear regression model to predict biological brain ageing and identifies age-related gene expression patterns linked to Parkinson's disease susceptibility.

bioRxiv · Dec 2, 2025 · PreprintNeuroscience

Single-cell analysis reveals MHCII expressing keratinocytes in pressure ulcers with worse healing outcomes

Dongqing Li, Shangli Cheng, Yu Pei, Pehr Sommar, Jaanika Kärner, Eva K. Herter, Maria A. Toma, Letian Zhang, Kim Pham, Yuen-Ting Cheung, Zhuang Liu, Xingqi Chen, Liv Eidsmo, Qiaolin Deng, Ning Xu

The paper uses single-cell transcriptomics to identify MHCII-expressing keratinocytes in pressure ulcers linked to poor healing outcomes.

Journal of Investigative Dermatology · Sep 15, 2021Peer-reviewedGenomics

Spatial RNA sequencing identifies robust markers of vulnerable and resistant human midbrain dopamine neurons and their expression in Parkinson's Disease

Julio Aguila Benitez, Shangli Cheng, Nigel Kee, Ming Cao, Menghan Wang, Qiaolin Deng, Eva Hedlund

The paper identifies stable gene markers distinguishing vulnerable SNc and resilient VTA dopamine neurons in humans and shows their expression changes in Parkinson's Disease.

Frontiers in Molecular Neuroscience · Jul 8, 2021Peer-reviewedNeuroscience

LCM-seq identifies robust markers of vulnerable and resistant human midbrain dopamine neurons

Julio Aguila Benitez, Shangli Cheng, Nigel Kee, Ming Cao, Qiaolin Deng, Eva Hedlund

This study identifies robust markers for human midbrain dopamine neurons using LCM-seq, showing they can distinguish SNc and VTA neurons in both human and mouse.

bioRxiv · Apr 3, 2020 · PreprintNeuroscience