Nicolas Coquelle

Structural basis of the two-photon photoactivation mechanism of orange carotenoid protein

The paper elucidates the structural basis of the two-photon photoactivation mechanism of orange carotenoid protein using a combination of structural and biochemical methods.

Integrated structural dynamics uncover new modes of B12 photoreceptor activation

The paper describes the photoactivation mechanism of the B12 photoreceptor CarH using structural and spectroscopic methods, revealing unique intermediates that drive tetramer dissociation.

Electron diffraction captures high-resolution structures from in vivo protein nanocrystals of Bacillus thuringiensis

This study uses electron diffraction techniques to determine the structure of in vivo protein nanocrystals from Bacillus thuringiensis, showing they are viable alternatives to X-ray free electron lasers.

Crystal structure of a bacterial photoactivated adenylate cyclase determined at room temperature by serial femtosecond crystallography

The paper determines the crystal structure of a bacterial photoactivated adenylate cyclase at room temperature using serial femtosecond crystallography and compares it with cryo structures to study structural changes upon light exposure.

De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals

The paper determines the structures of Cry11Aa and Cry11Ba toxins using serial femtosecond crystallography, revealing new insights into their in vivo crystallization patterns and toxicity.