Nicole Prince

Polygenic risk scores associate with asthma phenotypes and proteomic analyses implicate IL1R1 in two family-based studies

This study uses polygenic risk scores and proteomic analysis to identify genetic and molecular associations with asthma in two family-based cohorts, highlighting IL1R1's role in asthma pathogenesis.

Network Analysis Reveals Protein Modules Associated with Childhood Respiratory Diseases

The paper uses WGCNA to identify protein modules in 1-year-old children linked to respiratory diseases by age 6, showing associations with environmental and metabolomic factors.

The metabolic role of vitamin D in children's neurodevelopment: a network study

This study investigates the metabolic role of vitamin D in children's neurodevelopment using a network approach, finding associations between vitamin D deficiency and changes in tryptophan, linoleic, and fatty acid metabolism linked to ASD-related phenotypes.

OMICmAge: An integrative multi-omics approach to quantify biological age with electronic medical records

The paper develops OMICmAge, a multi-omics biomarker of biological age, and shows it outperforms existing markers in predicting chronic diseases and mortality.