Andrew Scott Clugston

SMRT-Tag enables low-input, single-molecule sequencing for simultaneous detection of genetic and epigenetic variations in human samples.

The paper characterizes chromatin accessibility and microRNA expression in nephron progenitor cells during kidney development, identifying changes in regulatory elements and microRNAs associated with key biological processes.

This study uses single-cell RNA sequencing to identify differential cell cycle activity in nephron progenitors during mouse kidney development, highlighting Birc5 as a potential key molecule in nephron patterning.

The paper presents miRNA profiling data for mouse nephron progenitors, identifying differentially expressed miRNAs and novel miRNAs, and provides them as a public resource for kidney development studies.