NeuroscienceNature AgingPeer-reviewed
Subcellular proteomics and iPSC modeling uncover reversible mechanisms of axonal pathology in Alzheimer's disease
Yifei Cai, Jean E. Kanyo, Rashaun S. Wilson…·Jaime Grutzendler
The paper uses subcellular proteomics and iPSC models to identify mTOR pathway activation in axonal spheroids and show its reversible role in Alzheimer's disease pathology.