Author

Iguaracy Pinheiro‐de‐Sousa

European Bioinformatics InstituteORCID 0000-0002-3956-3279Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Evangelia PetsalakiiD· 2 shared Amber Braker· 1 shared Angus Clark NairniD· 1 shared Anita J HuttneriD· 1 shared Girolamo GiudiceiD· 1 shared Hao-Ran Gan· 1 shared Hoang Kim Trinh· 1 shared Jaime GrutzendleriD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Evangelia PetsalakiORCID

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2 papers

Recent·Most cited

NeuroscienceNature AgingPeer-reviewedMar 10, 2025

Subcellular proteomics and iPSC modeling uncover reversible mechanisms of axonal pathology in Alzheimer's disease

Yifei Cai, Jean E. Kanyo, Rashaun S. Wilson…·Jaime Grutzendler

The paper uses subcellular proteomics and iPSC models to identify mTOR pathway activation in axonal spheroids and show its reversible role in Alzheimer's disease pathology.

26 citationstop 1%

humanmouse

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Systems BiologybioRxivPreprintNov 17, 2022

In silico network-based screening reveals candidates for endothelial dysfunction therapy

Iguaracy Pinheiro‐de‐Sousa, Girolamo Giudice, Miriam Helena Fonseca‐Alaniz…·José Eduardo Krieger

The paper identifies 17 candidate genes for endothelial dysfunction therapy using computational network analysis and in silico perturbation, with one target showing anti-inflammatory and antioxidant effects.

DOI 10.1101/2022.11.17.516953

humanATAC-seq

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