Saravanan Kolandaivelu

Dietary Sodium Deprivation Remodels the Serum Lipidome and Reveals Systemic Metabolic Adaptation in Rats

This study shows that dietary sodium deprivation alters the serum lipidome in rats, revealing metabolic adaptations related to lipid storage, membrane turnover, and mitochondrial function.

Dietary Sodium Restriction Reprograms Gut Microbial Fermentation and Reduces Host Energy Harvest

This study shows that reducing dietary sodium alters gut microbial fermentation and decreases host energy absorption in rats.

Aberrant Lipid Accumulation and Retinal Pigmental Epithelium Dysfunction in PRCD-deficient mice

This study investigates PRCD-deficient mice and finds increased retinal cholesterol and RPE dysfunction resembling AMD.

Nuclear NAD+-biosynthetic enzyme NMNAT1 facilitates survival of developing retinal neurons

This study shows that NMNAT1 deletion in developing murine retina causes severe photoreceptor and inner retinal neuron degeneration through multiple cell death pathways and metabolic disruptions.