Author

Venkatakrishna Rao Jala

University of LouisvilleORCID 0000-0002-4206-7305Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:metagenomics· 1 Organism:rat· 1

Frequent Co-Authors

Aniruddh MukunthiD· 1 shared Arul Jayaraman· 1 shared Audrey F. Duff· 1 shared Clint Cheng· 1 shared Cory L. Klemashevich· 1 shared Da Mi KimiD· 1 shared Gangqing HuiD· 1 shared Geoffrey I. SandleiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperCell Biology

Aniruddh MukunthORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dietary Sodium Restriction Reprograms Gut Microbial Fermentation and Reduces Host Energy Harvest

Joshua Cornman‐Homonoff, Kumaran M. Rajendran, Saravanan Kolandaivelu, Steven D. Coon, Justin Thomas Kupec, Lei Wang, Gangqing Hu, Venkatakrishna Rao Jala, Geoffrey I. Sandle, Vazhaikkurichi M. Rajendran

This study shows that reducing dietary sodium alters gut microbial fermentation and decreases host energy absorption in rats.

bioRxiv · Apr 21, 2026 · PreprintMicrobiology

The Nox2 NADPH oxidase regulates neutrophilic inflammation in the oral cavity

Shunying Jin, Richa A. Singhal, Jianzhu Luo, Yasmine H. Higgins, Kelley N Cooper, Marina Terekhova, Katherine Carey, Audrey F. Duff, Maxim N. Artyomov, Venkatakrishna Rao Jala, Rachel A. Idol, Michael T. Bailey, Mary C. Dinauer, Richard John Lamont, Juhi Bagaitkar

This study shows that Nox2 oxidase regulates neutrophilic inflammation in the oral cavity through Nrf2-dependent mechanisms, independent of its antimicrobial role.

Mucosal Immunology · Apr 8, 2026Peer-reviewedImmunology

NRF2-Dependent Anti-Inflammatory Activity of Indole via Cell Surface Receptor Signaling in Murine Macrophages

Clint Cheng, Siddanagouda R. Shivanagoudra, Aniruddh Mukunth, Sumathi Biradar, Yadeliz A. Serrano Matos, Cory L. Klemashevich, Da Mi Kim, Gus A. Wright, Sweta Ghosh, Venkatakrishna Rao Jala, Stephen H. Safe, Robert Christopher Alaniz, Arul Jayaraman

This study shows an indole conjugate inhibits inflammation in macrophages via NRF2-dependent surface receptor signaling.

bioRxiv · Dec 23, 2025 · PreprintCell Biology