Author

Yekai Wang

West Virginia University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Jianhai DuiD· 3 shared Aspen Tong· 1 shared Bo LiiD· 1 shared Bree R Nelson· 1 shared Connor NeviniD· 1 shared Daniel T. HassiD· 1 shared David SokoloviD· 1 shared Davide OrtolaniD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCell Biology

Jianhai DuORCID

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Author profile →

3 papers

Recent·Most cited

Nutrient Microenvironments Reprogram Pigment Epithelium Metabolism and Phenotype

Rayne R. Lim, Emily Zhao, Daniel T. Hass, Yekai Wang, Mark Eminhizer, Davide Ortolan, Sheldon Niernberger, Aspen Tong, Bree R Nelson, Marcos Nazario, Vishya Adipudi, Kapil Bharti, James B. Hurley, Jianhai Du, Jennifer R. Chao

This study examines how different nutrient microenvironments affect RPE cell phenotype, function, and metabolism in iPSC and fetal RPE, identifying key metabolic shifts and phenotypic changes.

bioRxiv · Jul 7, 2026 · PreprintCell Biology

Nuclear NAD+-biosynthetic enzyme NMNAT1 facilitates survival of developing retinal neurons

David Sokolov, Emily Sechrest, Yekai Wang, Connor Nevin, Jianhai Du, Saravanan Kolandaivelu

This study shows that NMNAT1 deletion in developing murine retina causes severe photoreceptor and inner retinal neuron degeneration through multiple cell death pathways and metabolic disruptions.

eLife · Dec 8, 2021Peer-reviewedMolecular Biology

Metabolic features of mouse and human retinas: rods vs. cones, macula vs. periphery, retina vs. RPE

Bo Li, Ting Zhang, Wei Liu, Yekai Wang, Rong Xu, Shaoxue Zeng, Rui Zhang, Siyan Zhu, Mark C. Gillies, Ling Zhu, Jianhai Du

The paper identifies metabolic differences between mouse and human retinas, cones vs. rods, macula vs. periphery, and retina vs. RPE, highlighting distinct metabolic pathways and nutrient exchange.

iScience · Oct 14, 2020Peer-reviewedNeuroscience