Author

J Austin Johnson

Koç UniversityORCID 0000-0002-8553-2465Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

Hasan DeMi̇rci̇iD· 2 shared A. BatyukiD· 1 shared Barış ÇakilkayaiD· 1 shared Bilge TosuniD· 1 shared Bradley B. TolariD· 1 shared Brandon Hayes· 1 shared Büşra YükseliD· 1 shared Cengizhan BüyükdağiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

Hasan DeMi̇rci̇ORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Crystal Structure of 3-Hydroxypropionyl-CoA Synthetase (ADP-forming) from Nitrosopumilus maritimus

J Austin Johnson, Bilge Tosun, Merve Yilmaz, Bradley B. Tolar, Yasuo Yoshikuni, Christopher A. Francis, Tzanko I. Doukov, Shun Yokoi, Soichi Wakatsuki A, Hasan DeMi̇rci̇

The paper reports the crystal structure of 3-Hydroxypropionyl-CoA Synthetase (ADP-forming) from Nitrosopumilus maritimus, revealing its subdomain organization and substrate-binding state.

Current Research in Structural Biology · Mar 17, 2026Peer-reviewedBiophysics

Case Study of High-Throughput Drug Screening and Remote Data Collection for SARS-CoV-2 Main Protease by Using Serial Femtosecond X-ray Crystallography

Ömür Güven, Mehmet Gül, Esra Beyarslan Ayan, J Austin Johnson, Barış Çakilkaya, Gozde Usta, Fatma Betül Ertem, Nurettin Tokay, Büşra Yüksel, Oktay Göcenler, Cengizhan Büyükdağ, Sabine Botha, Gihan K. Ketawala, Zhen Su, Brandon Hayes, , Hasan DeMi̇rci̇

This study demonstrates a high-throughput drug screening protocol using serial femtosecond X-ray crystallography for SARS-CoV-2 main protease, achieving 120 images/second with a new detector.

Crystals · Dec 17, 2021Peer-reviewedMolecular Biology