Author
Oslo University HospitalORCID 0000-0002-8563-2730Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Krister Vikedal, Natalia Berges, Ida Mathilde Marstein Riisnæs, Synnøve Brandt Ræder, Jørgen Vildershøj Bjørnholt, Magnar Bjørås, Kirsten Skarstad, Emily Helgesen, James Alexander Booth
This study identifies novel genes involved in ciprofloxacin-induced DNA supercompaction in E. coli using high-content imaging and machine learning.
Nucleic Acids Research · May 27, 2026Peer-reviewedMicrobiology
Ida Mathilde Marstein Riisnæs, Synnøve Brandt Ræder, Signe Simonsen, Krister Vikedal, Paul Hoff Backe, Line Johnsen, Magnar Bjørås, James Alexander Booth, Birthe Brandt Kragelund, Kirsten Skarstad, Emily Helgesen
This paper identifies a direct interaction between the RecBCD complex and the DNA sliding clamp in E. coli, showing its role in DNA repair and survival after DNA damage.
Nucleic Acids Research · May 27, 2026Peer-reviewedMicrobiology
Krister Vikedal, Synnøve Brandt Ræder, Ida Mathilde Marstein Riisnæs, Magnar Bjørås, James Alexander Booth, Kirsten Skarstad, Emily Helgesen
This study shows that ciprofloxacin induces DNA supercompaction in E. coli, requiring RecN and dependent on RecA, as part of a DNA damage response.
Nucleic Acids Research · May 13, 2025Peer-reviewedMicrobiology
Emily Helgesen, Frank Sætre, Kirsten Skarstad
The paper investigates the role of Topoisomerase IV in separating newly replicated bacterial chromosomes by showing its localization near the origin and movement pattern relative to replication machinery.
bioRxiv · Feb 14, 2020 · PreprintMolecular Biology