Musie S Ghebremichael

This study examines how the duration of initial HIV-1 viremia affects the functional properties of HIV-specific T cell receptors in individuals with HLA-B*58:01.

This study shows that PPARγ downregulation in colonic CD8+ T cells of people with HIV on ART leads to epithelial barrier disruption by promoting lipid uptake and apoptosis.

The paper identifies loss of transitional B cell tolerance and extrafollicular expansion of autoreactive B cells as a common mechanism driving autoimmunity in monogenic CVID.

Congenital T cell activation in CTLA4-deficient patients impairs transitional to follicular B cell maturation and can be rescued by CTLA4 replacement therapy in vivo.