GeneticsbioRxivPreprint
The spreading of facultative H3K9me3-heterochromatin drives congenital disease
Chen Wang, Wei Zhang, Xuelin Chen…·Fang-Lin Sun
This study identifies Cdk13's role in preventing H3K9me3-heterochromatin spreading, which causes congenital heart defects, and shows a compound can alleviate these defects in mice.
DOI 10.1101/2023.08.11.552907