Author

Fang-Lin Sun

Tongji UniversityORCID 0000-0003-4729-1610Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Yong-Hao Li· 2 shared Yuanya Jing· 2 shared Chen WangiD· 1 shared Chen Wang· 1 shared Cizhong JiangiD· 1 shared Dan Peng· 1 shared Feng SuniD· 1 shared Haowei WangiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersGenetics

Yong-Hao Li

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintAug 11, 2023

The spreading of facultative H3K9me3-heterochromatin drives congenital disease

Chen Wang, Wei Zhang, Xuelin Chen…·Fang-Lin Sun

This study identifies Cdk13's role in preventing H3K9me3-heterochromatin spreading, which causes congenital heart defects, and shows a compound can alleviate these defects in mice.

DOI 10.1101/2023.08.11.552907

mousestatistical model

𝕏 PostBluesky

GeneticsbioRxivPreprintNov 4, 2020

The Establishment of Transgenerational Epigenetic Inheritance in the C. elegans Germline is Mediated by Lipid Metabolism

Dan Peng, Chen Wang, Kai-Le Li…·Fang-Lin Sun

This study shows that lipid metabolism, via Pod-2 and vitellogenins, mediates the establishment of transgenerational epigenetic imprints in C. elegans germline.

3 citations

C. elegansDNA methylation

𝕏 PostBluesky