Molecular BiologyNucleic Acids ResearchPeer-reviewed
23S rRNA modifications stimulate catalytic activity and prevent the formation of alternative structures
Daniel S. D. Larsson, Aivar Liiv, Rya Ero…·M. Selmer
This study shows that 23S rRNA modifications enhance ribosome catalytic activity by stabilizing the peptidyl transferase center structure and preventing alternative conformations.
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