Conflicts between the DNA replication and repair machineries promote cell death in Gram-positive bacteria
Hannah Gaimster, Daniel Stevens, James W. Grimshaw, Julia Hubbard, Katarzyna M. Mickiewicz, Heath D. Murray, Charles Winterhalter
This study shows that inducing excessive DNA replication in Gram-positive bacteria causes cell death, suggesting a potential strategy for antimicrobial development by targeting replication and repair conflicts.
Microbiology · Nov 6, 2025Peer-reviewedMicrobiology