Author

Daniel Stevens

Newcastle UniversityORCID 0000-0002-5306-8864Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Daniel Stevens1 paper

Biology Disciplines

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Molecular Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Approach:experimental assay· 3 Assay:DNA methylation· 2 Research Focus:cell signaling & trafficking· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Charles WinterhalteriD· 3 shared Heath D. MurrayiD· 3 shared Aravindan IlangovaniD· 2 shared Elie Marchand· 2 shared Panos SoultanasiD· 2 shared Simone PelliciariiD· 2 shared Stepan FenykiD· 2 shared Hannah GaimsteriD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersMolecular Biology

Charles WinterhalterORCID

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3 papers

Recent·Most cited

Conflicts between the DNA replication and repair machineries promote cell death in Gram-positive bacteria

Hannah Gaimster, Daniel Stevens, James W. Grimshaw, Julia Hubbard, Katarzyna M. Mickiewicz, Heath D. Murray, Charles Winterhalter

This study shows that inducing excessive DNA replication in Gram-positive bacteria causes cell death, suggesting a potential strategy for antimicrobial development by targeting replication and repair conflicts.

Microbiology · Nov 6, 2025Peer-reviewedMicrobiology

SirA inhibits the essential DnaA:DnaD interaction to block helicase recruitment during Bacillus subtilis sporulation

Charles Winterhalter, Daniel Stevens, Stepan Fenyk, Simone Pelliciari, Elie Marchand, Panos Soultanas, Aravindan Ilangovan, Heath D. Murray

The paper identifies SirA as a repressor that inhibits DnaD-DnaA interaction, blocking helicase recruitment during Bacillus subtilis sporulation.

Nucleic Acids Research · Oct 25, 2022Peer-reviewedMolecular Biology

The DNA replication initiation protein DnaD is recruited to a specific strand of the Bacillus subtilis chromosome origin

Charles Winterhalter, Simone Pelliciari, Daniel Stevens, Stepan Fenyk, Elie Marchand, Nora Cronin, Panos Soultanas, Tiago R. D. Costa, Aravindan Ilangovan, Heath D. Murray

The paper identifies a specific ssDNA motif in Bacillus subtilis oriC that is preferentially bound by DnaD, facilitating strand-specific helicase recruitment for bidirectional replication.

bioRxiv · Apr 18, 2022 · PreprintMolecular Biology