Author

Romain Sigaud

Jena University HospitalORCID 0000-0002-8600-8876Unclaimed ORCID profile · follow to get notified of new preprints

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Romain Sigaud1 paper

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Akang Leonard Bassey· 1 shared Ashley Vardon· 1 shared Daniel Gharai· 1 shared Daniela KocheriD· 1 shared Darren Hargrave· 1 shared Florian SeltiD· 1 shared Grace CooksleyiD· 1 shared Hiba Hamdi· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Akang Leonard Bassey

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1 paper

Recent·Most cited

Cancer BiologyNeuro-OncologyPeer-reviewedOct 28, 2026

Standard treatment against paediatric BRAF-V600E glioma promotes senescence and sensitizes tumours to BCL-xL inhibition

Romain Guiho, Hiba Hamdi, Grace Cooksley…·Juan Pedro Martinez Barbera

This study shows that standard therapies for paediatric BRAF-V600E glioma induce senescence, which can be targeted by BCL-xL inhibitors to prevent tumour regrowth.

DOI 10.1093/neuonc/noag270

mousebulk RNA-seq

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