Author

義行高橋

University of UtahORCID 0000-0002-8612-9598Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Alana L. WelmiD· 2 shared Chieh-Hsiang Yang· 2 shared Hui YangiD· 2 shared Anders PitmaniD· 1 shared Apurva Srivastava· 1 shared Bryan Welm· 1 shared C Yang· 1 shared Elisabeth Brown· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Alana L. WelmORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Response to SMAC mimetics in patient-derived models of triple-negative breast cancer relies on RIPK1 activation

Elisabeth Brown, Paige Jensen, Chieh-Hsiang Yang, Emilio Cortes Sanchez, Zhengtao Chu, Hui Yang, Yi Qiao, 義行高橋, Apurva Srivastava, Bryan Welm, Jaime Fornetti, Alana L. Welm

This study identifies RIPK1 activation as a key determinant of response to SMAC mimetics in TNBC, showing that resistance is linked to impaired RIPK1 autophosphorylation and HOIP overexpression.

bioRxiv · Oct 28, 2026 · PreprintCancer Biology

DS5: An Open-Source Framework for Standardized High-Throughput Drug Screening Data Storage, Analysis, and Drug Prioritization

Hui Yang, James Lubkowitz, Gabor Marth, Samuel Henry Cheshier, Chieh-Hsiang Yang, Alana L. Welm, Philip J. Moos, Xiaomeng Huang, 義行高橋

DS5 is an open-source framework that standardizes HTS data storage, analysis, and drug prioritization, validated against public benchmarks and applied in clinical settings.

bioRxiv · Sep 28, 2026 · PreprintBioinformatics

cuBayes: GPU accelerated FreeBayes that achieves 1-minute whole-genome SNV calling while maintaining algorithmic semantics

Anders Pitman, C Yang, 義行高橋

cuBayes accelerates whole-genome SNV calling using GPU acceleration, reducing analysis time from hours to minutes while maintaining high concordance with CPU results.

bioRxiv · Jun 16, 2026 · PreprintBioinformatics