Moe Ishikawa

In situ structure determination of Respiratory Supercomplexes and ATP synthase oligomers in mammalian mitochondrial inner membrane.

The paper determines the in situ structures of respiratory supercomplexes and ATP synthase oligomers in bovine heart mitochondria using cryoEM, revealing new structural arrangements and their implications for mitochondrial function.

The Na+-pumping mechanism driven by redox reactions in the NADH-quinone oxidoreductase from Vibrio cholerae relies on dynamic conformational changes

This study identifies five conformational states of Na+-NQR in Vibrio cholerae using mutants and inhibitors, revealing that 2Fe-2S reduction drives Na+ translocation through structural rearrangements.