Hideto Miyoshi

Mycothiazole enables structural characterization of entire ubiquinone-accessing tunnel in mitochondrial respiratory complex I

This study uses mycothiazole to stabilize and reveal the structure of the UQ-accessing tunnel in mitochondrial complex I, showing a hybrid conformational state.

Structure–activity relationship of antimycin A-like compounds as photosystem II inhibitors

This study examines the structure-activity relationship of antimycin A-like compounds on photosystem II, identifying key structural features and proposing tentative binding models.

In situ structure determination of Respiratory Supercomplexes and ATP synthase oligomers in mammalian mitochondrial inner membrane.

The paper determines the in situ structures of respiratory supercomplexes and ATP synthase oligomers in bovine heart mitochondria using cryoEM, revealing new structural arrangements and their implications for mitochondrial function.

The Na+-pumping mechanism driven by redox reactions in the NADH-quinone oxidoreductase from Vibrio cholerae relies on dynamic conformational changes

This study identifies five conformational states of Na+-NQR in Vibrio cholerae using mutants and inhibitors, revealing that 2Fe-2S reduction drives Na+ translocation through structural rearrangements.