Author
Lawrence D. True
University of WashingtonORCID 0000-0002-8621-9569Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2024-2026 · peak 4/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author links7 papers
Recent·Most cited
- PathologybioRxivPreprint
Scalable 3D cell-interaction analysis via supercell graphs for prostate cancer risk stratification
Yujie Zhao, Sarah S. L. Chow, Renao Yan…·Jonathan T.C. Liu
SCALE3D improves prostate cancer risk prediction by analyzing 3D cell interactions through supercell graphs, outperforming traditional features and reducing computational demands.
DOI 10.64898/2026.07.07.736891 - BioengineeringNature MethodsPeer-reviewed
3D pathology-guided microdissection
Huai-Ching Hsieh, Gan Gao, Qinghua Han…·Jonathan T.C. Liu
This paper introduces a 3D microdissection method combining CNC milling and light-sheet microscopy to study tumor evolution in complex 3D structures.
3 citationstop 4% - PathologyModern PathologyPeer-reviewed
Detection of prostate cancer in 3D pathology datasets via generative immunolabeling
Robert Serafin, Jennifer Salguero López, SP Chow…·Jonathan T.C. Liu
This paper develops a 3D computational pipeline called SIGHT to detect prostate cancer in pathology datasets using generative immunolabeling, achieving an F1 score comparable to pathologist agreement.
- PathologybioRxivPreprint
Deep-learning triage of 3D pathology datasets for comprehensive and efficient pathologist assessments
Gan Gao, Renao Yan, Andrew H. Song…·Jonathan T.C. Liu
CARP3D uses deep learning to prioritize high-risk 2D sections in 3D pathology data, improving disease detection while reducing pathologist workload.
6 citations - Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewed
Single Cell Analysis of Treatment-Resistant Prostate Cancer: Implications of Cell State Changes for Cell Surface Antigen Targeted Therapies
Samir Zaidi, Jooyoung Park, Joseph Minhow Chan…·Charles L. Sawyers
The paper uses single-cell analysis to study how cell surface antigen expression changes in treatment-resistant prostate cancer, revealing transcriptional heterogeneity and shared gene regulatory networks between NEPC and SCLC.
- BiophysicsbioRxivPreprint
Imaging and quantification of prostate cancer-associated bone by polarization-sensitive optical coherence tomography
Chris Zhou, Naomi Jung, Samuel Xu…·Michael Cox
This study uses PS-OCT to differentiate bone tissue types in prostate cancer metastases by analyzing collagen organization and quantifying structural features.