Author
Faisal Mahmood
Broad InstituteORCID 0000-0001-7587-1562Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2021-2026 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author links9 papers
Recent·Most cited
- PathologybioRxivPreprint
Scalable 3D cell-interaction analysis via supercell graphs for prostate cancer risk stratification
Yujie Zhao, Sarah S. L. Chow, Renao Yan…·Jonathan T.C. Liu
SCALE3D improves prostate cancer risk prediction by analyzing 3D cell interactions through supercell graphs, outperforming traditional features and reducing computational demands.
DOI 10.64898/2026.07.07.736891 - Cancer BiologyCell Reports MedicinePeer-reviewed
Epstein-Barr Virus Orchestrates Spatial Reorganization and Immunomodulation within the Classic Hodgkin Lymphoma Tumor Microenvironment
Yao Yu Yeo, Huaying Qiu, Yunhao Bai…·Sizun Jiang
This study uses spatial multi-omics to compare EBV-positive and EBV-negative cHL, identifying distinct TME features and immunological signatures linked to EBV.
3 citations - PathologybioRxivPreprint
Deep-learning triage of 3D pathology datasets for comprehensive and efficient pathologist assessments
Gan Gao, Renao Yan, Andrew H. Song…·Jonathan T.C. Liu
CARP3D uses deep learning to prioritize high-risk 2D sections in 3D pathology data, improving disease detection while reducing pathologist workload.
6 citations - BioinformaticsbioRxivPreprint
spEMO: Leveraging Multi-Modal Foundation Models for Analyzing Spatial Multi-Omic and Histopathology Data
Tianyu Liu, Tinglin Huang, Tong Ding…·Hongyu Zhao
spEMO integrates histopathology and spatial multi-omic data using foundation models, improving performance in spatial analysis and medical report generation.
6 citations - BioinformaticsbioRxivPreprint
Deep Learning-based Modeling for Preclinical Drug Safety Assessment
Guillaume Jaume, Simone de Brot, Andrew H. Song…·Faisal Mahmood
This paper introduces TRACE, a deep learning model for automated liver histopathology assessment in preclinical drug safety, achieving higher concordance than pathologists in lesion scoring and dose-response analysis.
- BioinformaticsbioRxivPreprint
AI-driven Discovery of Morphomolecular Signatures in Toxicology
Guillaume Jaume, Thomas Peeters, Andrew H. Song…·Faisal Mahmood
This paper introduces GEESE, an AI model that imputes morphomolecular signatures in toxicology data, linking gene expression changes to drug-induced liver injuries.
4 citations - BioinformaticsNature Biomedical EngineeringPeer-reviewed
Aggregation Tool for Genomic Concepts (ATGC): A deep learning framework for somatic mutations and other sparse genomic measures
Jordan Anaya, John-William Sidhom, Faisal Mahmood, Alexander Spyridon Baras
The paper introduces a deep learning framework for genomic data that aggregates and predicts somatic mutations and other sparse genomic measures using attention-based multiple instance learning.
20 citations - BioinformaticsbioRxivPreprint
Benchmarking artificial intelligence methods for end-to-end computational pathology
Narmin Ghaffari Laleh, Hannah Sophie Muti, Chiara Maria Lavinia Loeffler…·Jakob Nikolas Kather
This study benchmarks AI methods for end-to-end computational pathology, showing ResNet and ViT outperform MIL and CLAM in mutation prediction but not in tumor subtyping.