Author

Mohamed Eldeeb

Lund UniversityORCID 0000-0002-8636-2189Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1

Frequent Co-Authors

David BryderiD· 2 shared Eva Erlandsson· 2 shared Shamit SonejiiD· 2 shared Amol Sanjay UgaleiD· 1 shared Cecilia LaterzaiD· 1 shared Derrick J. RossiiD· 1 shared Göran KarlssoniD· 1 shared Joan YuaniD· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBioinformatics

David BryderORCID

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2 papers

Recent·Most cited

Nabo - a framework to define leukemia-initiating cells and differentiation in single-cell RNA-sequencing data

Parashar Dhapola, Mohamed Eldeeb, Amol Sanjay Ugale, Rasmus Olofzon, Eva Erlandsson, Shamit Soneji, David Bryder, Karlsson Göran

Nabo maps cells from one population to the most similar cells in a reference population, improving accuracy in identifying tumor-initiating cells in single-cell RNA-Seq data.

bioRxiv · Sep 30, 2020 · PreprintBioinformatics

HSCs contribute actively to native multilineage hematopoiesis but with reduced differentiation capacity upon aging

Petter Säwén, Mohamed Eldeeb, Eva Erlandsson, Trine Ahn Kristiansen, Cecilia Laterza, Zaal Kokaia, Göran Karlsson, Joan Yuan, Shamit Soneji, Pankaj Kumar Mandal, Derrick J. Rossi, David Bryder

This study shows that adult HSCs contribute to all blood lineages in steady state but decline in contribution with age due to reduced differentiation capacity.

eLife · Dec 18, 2018Peer-reviewedDevelopmental Biology