Author

Bryan R. Cullen

Duke UniversityORCID 0000-0002-8638-6850Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:gene regulatory network inference· 2 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1 Assay:multiome· 1

Frequent Co-Authors

Hal P. BogerdiD· 2 shared Kevin TsaiiD· 2 shared Ann EmeryiD· 1 shared Cecilia Martinez CamposiD· 1 shared Christopher L. HolleyiD· 1 shared David CourtneyiD· 1 shared Edward M. KennedyiD· 1 shared Ishak D. Irwan· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

9 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Hal P. BogerdORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mapping of pseudouridine residues on cellular and viral transcripts using a novel antibody-based technique

Cecilia Martinez Campos, Kevin Tsai, David Courtney, Hal P. Bogerd, Christopher L. Holley, Bryan R. Cullen

The paper introduces PA-{Psi}-seq, a technique to map pseudouridine residues on cellular and viral transcripts, and shows that HIV-1 transcripts are not affected by PUS enzyme inactivation.

RNA · Aug 10, 2021Peer-reviewedMolecular Biology

Tax induces the recruitment of NF-kB to unintegrated HIV-1 DNA to rescue viral gene expression and replication

Ishak D. Irwan, Bryan R. Cullen

The paper shows Tax rescues HIV-1 replication by recruiting NF-kB to unintegrated viral DNA, enabling transcription and epigenetic changes, and describes effective IN-lentiviral vectors.

Journal of Virology · Apr 19, 2021Peer-reviewedMolecular Biology

Epitranscriptomic addition of m6A regulates HIV-1 RNA stability and alternative splicing

Kevin Tsai, Hal P. Bogerd, Edward M. Kennedy, Ann Emery, Ronald I. Swanstrom, Bryan R. Cullen

This paper shows that m6A methylation regulates HIV-1 RNA stability and alternative splicing through YTHDC1 and YTHDF2.

bioRxiv · Feb 23, 2021Molecular Biology