Cancer BiologybioRxiv
Natural killer cell cytotoxicity shapes the clonal evolution of B cell leukaemia
Michelle C. Buri, Mohamed R. Shoeb, Aleksandr Bykov…·Eva M. Putz
This study shows NK cells influence all phases of cancer immunoediting in B-ALL, promoting resistant clones through selective pressure and identifying LY6E as a marker of poor prognosis.