Altered neural activity in the mesoaccumbens pathway underlies impaired social reward processing in Shank3-deficient rats
Marie Barbier, Keerthi Thirtamara Rajamani, Shai Netser, Shlomo Wagner, Hala Harony‐Nicolas
This study shows that Shank3-deficient rats have altered neural activity in the mesoaccumbens pathway, leading to impaired social reward processing, and that manipulating VTA activity can normalize behavior.
Advanced Science · Mar 14, 2025Peer-reviewedNeuroscience